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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DOPEY2 All Species: 36.97
Human Site: S1659 Identified Species: 62.56
UniProt: Q9Y3R5 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y3R5 NP_005119.2 2298 258184 S1659 G A T K G S S S V Y F K T T K
Chimpanzee Pan troglodytes XP_531552 2298 258112 S1659 G A T K G S S S V Y F K T T K
Rhesus Macaque Macaca mulatta XP_001084653 2286 256620 S1647 G A T K G S S S V Y F K T T K
Dog Lupus familis XP_544874 2297 257913 S1659 G A T K G S S S V Y F K T T K
Cat Felis silvestris
Mouse Mus musculus Q3UHQ6 2295 257491 S1658 G A T K G S S S V Y F K T T K
Rat Rattus norvegicus XP_001055500 2294 257490 S1657 G A T K G S S S V Y F K T T K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512569 2247 251024 S1613 S A T R A S S S V Y F K A T K
Chicken Gallus gallus XP_001232723 2283 257889 S1645 G T T K G S S S V Y F K A T K
Frog Xenopus laevis Q642P2 2270 256829 S1629 G T I K A S S S V Y F K S T K
Zebra Danio Brachydanio rerio NP_956904 817 86774 S200 P L V R L P A S L F I V A H F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZBE8 2599 291169 R1939 A V L S H L P R I M S S V A A
Honey Bee Apis mellifera XP_395999 2434 273219 A1807 S L S T L W Q A V L A T K D N
Nematode Worm Caenorhab. elegans Q9XW10 2417 267134 S1722 I V P I G T N S Q L R R L V L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03921 1698 194669 F1081 G S N L K G D F I Q S V V S N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 94.8 89.9 N.A. 86.4 86.4 N.A. 73.9 75.2 69 21.9 N.A. 27.6 32.1 22.3 N.A.
Protein Similarity: 100 99.7 96 94.6 N.A. 92.4 92.5 N.A. 83 85.4 82 28.7 N.A. 47 53.2 40.9 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 73.3 86.6 73.3 6.6 N.A. 0 6.6 13.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 80 86.6 80 33.3 N.A. 6.6 20 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 50 0 0 15 0 8 8 0 0 8 0 22 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 8 65 0 0 0 8 % F
% Gly: 65 0 0 0 58 8 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 8 0 8 8 0 0 0 0 15 0 8 0 0 0 0 % I
% Lys: 0 0 0 58 8 0 0 0 0 0 0 65 8 0 65 % K
% Leu: 0 15 8 8 15 8 0 0 8 15 0 0 8 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 15 % N
% Pro: 8 0 8 0 0 8 8 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 8 0 8 8 0 0 0 0 0 % Q
% Arg: 0 0 0 15 0 0 0 8 0 0 8 8 0 0 0 % R
% Ser: 15 8 8 8 0 65 65 79 0 0 15 8 8 8 0 % S
% Thr: 0 15 58 8 0 8 0 0 0 0 0 8 43 65 0 % T
% Val: 0 15 8 0 0 0 0 0 72 0 0 15 15 8 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 65 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _